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Anti-aging medicines: the next-generation tools for continuing a working career


The thing that causes aging is damage to the DNA. There is a self-destruction process in cells. But somehow, that self-destruction doesn't always work as it should. If that self-destruction doesn't work, the result is that zombie cells are left in the body. Sometimes the thing that causes failure in the cell's self-destruction process is in genomes where telomers are turned short. Telomers are the first and last parts of DNA. And the self-destruction mode of the cells is hidden in those telomers. So if the self-destruction can connect back to the zombie cell's DNA, that destroys those harmful cells.

Another way to clean those harmful zombie cells away is to use their shell antigens. Some of the zombie cells are not similar to regular cells. The zombie cell is hairy, and that means some mark proteins will touch those cells better than wealthy and functioning cells. Those proteins can mark the cell so that the immune system destroys it. Zombie cells play a key role in cancer cases. Those cells are turning into cancer cells.

A zombie cell means that the cell's mission is over. But they don't "want to die". That means the nanotechnical medicines can contain some kind of chemical mark or antigen that touches only those zombie cells. And that helps the immune system destroy them.

Artificial intelligence is the ultimate tool for the R&D process in medicine. The term anti-aging medicine means medicines that remove zombie cells from the body. Or maybe in the future, those medicines can fix damaged DNA. The difference between those medicines and some cosmetic products is that those medicines affect something that causes aging. And the most conventional way is to just mark zombie cells for immune defense so that it can remove cells that have completed their mission from the body.



"Researchers have utilized AI to discover new senolytic compounds that can suppress age-related processes, such as cancer and inflammation. By training deep neural networks on experimental data, they were able to identify three potent drug candidates from a chemical pool of over 800,000 molecules, promising superior clinical properties to existing senolytics." (ScitechDaily.com/Artificial Intelligence Unlocks New Possibilities in Anti-Aging Medicine)


Zombie cell

The problem with zombie-cell markers is that they can mark the wrong cells. And that thing can cause catastrophic situations.


Genetic therapy, where damaged DNA will be replaced by fresh DNA, can be the answer to an extremely long life. But the requirement for that therapy is that there be fresh DNA that the system can use to replace the DNA from the cells. The problem is that the DNA must be taken at a very young age. The PCR Polymerase Chain Reaction can multiply that DNA.

But AI-controlled nanotechnology can also make the DNA copy by using a digital database. The DNA is in digital mode, and then nanorobots are making that DNA by using similar systems that are used in protein and complex chemical manufacturing. Those systems are in use in medical factories. Nanotechnology and AI can also make it possible to create artificial DNA. That thing requires complete knowledge of the functions of every DNA base pair. But AI and CRISPR can make this kind of thing possible sooner than we ever imagined.

The problem with anti-aging medicines is that they should fix genomes or DNA. The system can replace damaged DNA by using fresh DNA. There is a possibility that the DNA that was injected into the cells contains a sequence that makes those infected cells immune against some cytostatic or virus, and that helps to remove non-infected cells from the body. Here I mean that the cells' genome is not changed and will be easier to remove.

But making a person young again is a more complicated process than just removing zombie cells from the human body. The system must remove damaged DNA and then inject new DNA into those cells. The problem is that there is a lot of DNA that is needed. The thing that could make the process where the DNA is changed in the cell's nucleus possible could be genetically engineered immune cells, like macrophages or B lymphocytes. Those manipulated immune cells can be injected into a human's bone marrow, and then they can produce artificial viruses. Or change the DNA in the cells.

Advanced nanotechnology also makes it possible to engineer the DNA of bacteria or any other cell. That genetically engineered immune cell can produce DNA that it can use to make artificial viruses. Genetically engineered macrophages can change the DNA in the cell's nucleus. If we want to make people young again, we should replace damaged DNA with fresh DNA. There is a possibility that the DNA that replaces the old DNA involves a sequence that makes "infected cells" immune to some medicine or viruses. Then the cells that are not infected will be destroyed.


https://scitechdaily.com/artificial-intelligence-unlocks-new-possibilities-in-anti-aging-medicine/


https://scitechdaily.com/anti-aging-medicines-seek-to-eliminate-zombie-cells-but-could-this-be-dangerous/


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